Permethrin is a synthetic pyrethroid compound with established insecticidal and ectoparasiticidal activity. Pharmaceutical-grade material can be used as an active pharmaceutical ingredient (API) in appropriately formulated topical preparations.

Permethrin is commonly associated with topical products used for the treatment of scabies and head-lice infestations. The finished product's concentration, formulation, directions for use, labeling, and regulatory status depend on the intended indication and the requirements of the relevant health authority.

As a pharmaceutical raw material, Permethrin should be manufactured, tested, stored, and handled according to appropriate pharmaceutical quality systems and regulatory requirements. WHO notes that pharmaceutical quality standards and GMP requirements are important for medicines and pharmaceutical ingredients.

The physicochemical characteristics of permethrin can vary according to the cis/trans isomer ratio and grade. WHO specifications describe, for example, 25:75 and 40:60 cis:trans technical-grade materials as distinct specifications. Therefore, your product listing should use the exact specification of your supplied pharmaceutical-grade material rather than a generic technical-grade specification.

Key Features

• Pharmaceutical Grade Active Ingredient
• High-Purity Permethrin
• Synthetic Pyrethroid
• Suitable for Qualified Pharmaceutical Manufacturing
• Intended for Topical Pharmaceutical Formulations
• Consistent Quality When Supplied with Appropriate Documentation
• Suitable for Professional & Industrial Pharmaceutical Applications
• COA/TDS/SDS Available According to Product Supply

Applications / Uses

Pharmaceutical & Topical Formulations

Appropriately formulated Permethrin is used in products intended for:

• Scabies treatment
• Head-lice treatment
• Topical ectoparasite-control preparations

Permethrin's established pharmaceutical use includes topical treatment of certain ectoparasitic infestations. WHO also identifies it as an insecticide.

Pharmaceutical Manufacturing

Pharmaceutical-grade Permethrin may be used as an API in the manufacture of approved topical preparations.

The final formulation, concentration, dosage form, labeling, and therapeutic claims must be established according to the applicable pharmaceutical regulations and approved product requirements.

Product Forms

Depending on the manufacturer and formulation requirements, Permethrin may be incorporated into products such as:

• Topical Cream
• Topical Lotion
• Topical Emulsion
• Other Approved Topical Preparations

The raw material itself is not a finished medicine and should not be applied directly to the skin without being formulated into an appropriately approved product.

Handling & Storage

• Store in a cool, dry, well-ventilated area.
• Keep the original container tightly closed.
• Protect from excessive heat, moisture, and direct sunlight.
• Avoid unnecessary exposure during handling.
• Use appropriate pharmaceutical manufacturing controls.
• Follow the manufacturer's SDS, TDS, and COA.
• Keep away from unauthorized personnel and children.

Safety Information

Permethrin is an active insecticidal substance and should be handled as a controlled pharmaceutical/chemical raw material.

• For professional pharmaceutical manufacturing use.
• Do not use the raw material directly as a medicine.
• Do not ingest.
• Avoid unnecessary skin and eye contact with the concentrated raw material.
• Avoid inhalation of dust or vapors where applicable.
• Use suitable gloves, protective clothing, and eye protection during handling.
• Follow the manufacturer's SDS and applicable occupational-safety requirements.
• Finished medicinal products should only be manufactured and used according to their approved formulation and labeling.